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Results:
533 patients achieved a mean BED of 206 Gy (range 158-266) with LDREBRT compared to 194 Gy (range 140-260) for 919 patients treated with LDRM (p=0.000). There was no significant difference between the mean AUASS of patients who achieved a BED of between 140-169 Gy treated with either LDREBRT or LDRM at any follow-up interval. There was a significant difference in mean AUASS among the group treated to a BED of 170-209 at the 6 month interval, LDREBRT mean AUASS of 11.7 versus 13.1 for LDRM (p=0.02). In addition, a significant difference was found in the group treated to a BED of 210-239, with the mean AUASS of LDREBRT 11.1 versus 14.7 at six months (p=0.000). No difference in mean AUASS was noted for the relatively small group (45 patients) achieving a BED of 240-270.
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