Abstract # 2877 Surviving Fraction (SF2) and Clonogen Cell Density (CCD) are the Dominant Predictors of Tumor Control Probability (TCP) in High Grade Glioma

Presenter: Ahmad, Salahuddin

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Materials/Methods:
IMRT plans were generated for twenty patients with high grade glioma at the New York University Medical Center. The prescribed dose was 59.4 Gy at 1.8 Gy per fraction. Using the Niemierko method and the Munro-Gilbert hypothesis, TCP was calculated for α/β of 3, 5, 8 and 10, SF2 of 0.3, 0.4, 0.5, 0.6, 0.7, 0.8 and CCD of 100 to 2 X 108 cells/cc.