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Materials/Methods:
One hundred forty-seven patients who underwent prostate brachytherapy between January 2003 and February 2006 met the following eligibility criteria: (1) Treatment with 125I brachytherapy to a prescribed dose of 160 Gy +/- hormones without supplemental external beam radiation therapy; (2) Identification as potent prior to the time of implantation based on a score ≥2 on the physician-assigned Mount Sinai Erectile Function Score (MSEFS) and a score ≥16 on the abbreviated International Index of Erectile Function patient assessment; (3) Minimum follow-up of 12 months. Median follow-up was 25.7 months. The penile bulb was contoured on the postimplant CT scan at 3 mm intervals, and the volume of penile bulb receiving 100% of the prescription dose (V100) and the dose to the hottest 5% of the penile bulb (D5) were recorded. The right and left neurovascular bundles and surrounding fascial planes were outlined as triangular structures bounded by the posterolateral edge of the prostate, the levator ani muscle, and the rectal wall. For each neurovascular bundle structure, the volumes receiving 100% and 150% of the prescription dose (NVB V100 and V150) were recorded. Postimplant impotence was defined as MSEFS <2.
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